Safe has partnered with Circle to integrate USDC into its ecosystem

Safe, an on-chain asset custody protocol, has announced a collaboration with Circle today to integrate USDC into its network as the preferred stablecoin for institutional self-custody and on-chain treasury ￰0￱ partnership aims to align treasury operations, compliance workflows, and liquidity access for institutions that seek reliable and secure custodial infrastructure. Circle’s USDC, a fully backed, regulated stablecoin infrastructure, will be integrated with Safe’s programmable, policy-aware smart contracts to create an institutional-grade solution for managing fiat currency ￰1￱ collaboration will create an end-to-end experience comprising onboarding, policy-based approvals, role-based spending controls, and direct access to DeFi ￰2￱ to utilize Circle’s CCTP architecture in eliminating inefficiencies Circle’s Cross-Chain Transfer Protocol (CCTP), which enables native USDC minting and burning across supported blockchains, will allow balances to move seamlessly between networks without the need for wrapped ￰3￱ revealed in its press release that the CCTP architecture will natively enable users to perform cross-chain treasury movements, eliminating inefficiencies associated with centralized intermediaries. 📣 MAJOR NEWS: @safefndn and @circle are partnering to accelerate @USDC adoption on Safe smart accounts and establish @safe as the institutional standard for self-custody & DeFi 🟢 Over $57 billion in USDC has moved through Safe since ￰4￱ the past 18 months, institutional… ￰5￱ — ￰6￱ (@safe) October 14, 2025 Safe recently launched Safe Labs, a wholly owned subsidiary tasked with delivering enterprise-grade self-custody ￰7￱ platform guarantees uptime and service-level agreements (SLAs) and oversees the SafeWallet ￰8￱ Analytics data indicate that Safe has a total locked value exceeding $60 billion and processes approximately 0.53% of all Ethereum ￰9￱ leads in the number of transactions within the custody protocol by chain, with 62.32%.

The firm has also recorded approximately 724 billion transactions across all chains, with Q1 2025 alone accounting for 189.6 billion, a 65% quarter-over-quarter ￰10￱ revealed that over $57 billion in USDC has moved through its platform since 2023, with $25.3 billion in USDC transfers made in ￰11￱ on-chain custody protocol now secures $2.5 billion in ￰12￱ has crossed half a billion in transaction volume, establishing itself as a platform for institutional stablecoin operations. “Institutional money flows into self-custody infrastructure and DeFi, and institutions need secure, scalable tools to keep ￰13￱ Circle, we’re positioning USDC as a core pillar of the Safe ecosystem, so Safe becomes a home for institutional stablecoin DeFi.” – Lukas Schor, Co-founder of Safe and the President of the Safe Ecosystem ￰14￱ stock has shed over 10% this week Safe collaboration with Circle came just three months after Circle’s New York Stock Exchange ￰15￱ stock’s current market cap stands at $31.09 billion, and it has a 61.12% stock return over the past ￰16￱ covered the IPO story , noting the opening price for the first trading day at $69, which surpassed previous predictions of the price discovery.

Circle’s stock rallied during its debut on the NYSE, briefly climbing to $84.92, over 174% above its IPO price of $31. Soon after the trading started, excessive volatility led to a trading halt after triggering a limit-up circuit ￰17￱ traders reported an inability to buy shares as the price rallied in minutes. Today, the stock is trading at $133.90, representing a 2.53% decline over the past 24 hours and a gain of over 10% over the past ￰18￱ Razzaghi, Circle’s Chief Commercial Officer, noted that institutions typically seek trusted and scalable infrastructure to manage their capital as they transition ￰19￱ acknowledged that Safe has already proven itself as a reliable platform for USDC adoption at ￰20￱ collaboration between the custody protocol and Circle creates a secure, composable, and compliant capital management ￰21￱ suggested that the model could set a precedent for institutional adoption of on-chain finance, especially as treasury management shifts from custodial intermediaries to programmable, auditable self-custody ￰22￱ Bybit now and claim a $50 bonus in minutes